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They can be used for various cardiovascular conditions, including myocardial infarction, heart failure, fibrosis, ischemic disease, cardiomyopathy, among others. Here's how they work:
- Regenerating Damaged Heart Tissue: After a heart attack or other cardiac injury, heart muscle cells (cardiomyocytes) are often damaged or lost. Umbilical cord stem cells release growth factors stimulating the repair, regeneration and formation of new cardiomyocytes improving the heart's structural integrity.
- Promoting Angiogenesis (Formation of New Blood Vessels): this process encourages the development of new blood vessels, enhancing blood flow to oxygen-deprived areas of the heart. Improved circulation supports tissue recovery and reduces further damage.
- Reducing Inflammation and Immune Modulation: Chronic inflammation contributes to the progression of heart disease and heart failure. Umbilical cord stem cells release anti-inflammatory cytokines and also modulate immune responses, preventing the immune system from attacking healthy heart tissue.
- Improving Heart Function: By repairing tissue, forming new blood vessels, and reducing inflammation, umbilical cord stem cells improve the heart's contractility and efficiency, alleviating symptoms of heart failure and enhancing overall quality of life.